Efficient Ball Mill Procedure In The Green Asymmetric Aldol Reaction

the organocatalytic activity of the methyl ester of (s)-proline-(s)-phenylalanine, (s,s)-2, in the asymmetric aldol reaction between cyclohexanone and acetone with various aromatic aldehydes under solvent-free conditions in a ball mill has been evaluated.,-dipeptide (s,s)-2 catalyzed the stereoselective formation of the expected aldol products, with higher diastereo- and.